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	<title>FIRST SEMESTER &#8211; Master Neuroscience in Athens</title>
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	<title>FIRST SEMESTER &#8211; Master Neuroscience in Athens</title>
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		<title>Research Training Exercise (Laboratory Rotation) &#8211; Technical Courses I</title>
		<link>https://masterneuroscience.gr/course/research-training-exercise-laboratory-rotation-technical-courses-i/</link>
		
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		<pubDate>Fri, 02 Feb 2024 10:00:06 +0000</pubDate>
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					<description><![CDATA[Teaching hours This is a 1st semester course of about 8 weeks that corresponds to 10 ECTs and 39 total hours of lectures and approximately 320 total hours of laboratory presence/training. The course is subdivided into the following parts: Technical courses I: Methodological approaches in Neuroscience, Statistics (SPSS, R programming, graphpad) Technical courses II: Molecular&#8230; <a class="continue" href="https://masterneuroscience.gr/course/research-training-exercise-laboratory-rotation-technical-courses-i/">Continue Reading<span> Research Training Exercise (Laboratory Rotation) &#8211; Technical Courses I</span></a>]]></description>
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					<h2 class="elementor-heading-title elementor-size-default">Teaching hours</h2>				</div>
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									<p>This is a 1<sup>st</sup> semester course of about 8 weeks that corresponds to 10 ECTs and 39 total hours of lectures and approximately 320 total hours of laboratory presence/training.</p>								</div>
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									<p><strong>The course is subdivided into the following parts:</strong></p>								</div>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text"><strong>Technical courses I: Methodological approaches in Neuroscience, Statistics (SPSS, R programming, graphpad)</strong></span>
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											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text"><strong>Technical courses II: Molecular Biology-Omics</strong></span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text"><strong>Technical courses III: Methodological approaches in Neuroscience, Elements of Bioinformatics (big data bases)</strong></span>
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					<h2 class="elementor-heading-title elementor-size-default">Co-ordinators</h2>				</div>
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							<svg xmlns="http://www.w3.org/2000/svg" width="19" height="19" viewBox="0 0 19 19" fill="none"><path d="M17.1328 16L12.8203 18.8359L9.39844 12.9297L5.90625 18.8359L1.54688 15.9531L6 11.0078L0.140625 9.57812L1.73438 4.96094L7.33594 7.39844L6.91406 0.976562H11.9531L11.5312 7.39844L17.0391 4.96094L18.6328 9.57812L12.7734 11.0078L17.1328 16Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">Nikos <strong> Fyllas</strong></span>
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									<p>Assistant Professor, Department of Biology, National and Kapodistrian University of Athens</p>								</div>
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										<span class="elementor-icon-list-text">Spiros <strong>Efthimiopoulos</strong> Ph.D</span>
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									<p>Professor, Department of Biology, National and Kapodistrian University of Athens</p>								</div>
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
				</div>
				<div class="elementor-element elementor-element-45cc4c7 elementor-widget elementor-widget-text-editor" data-id="45cc4c7" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
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									<p>This course is intended to cover the basic statistical principles usually applied in the biological sciences. The goal of the course is to provide the students with the ability to choose and apply the appropriate statistics for their studies.</p>								</div>
				</div>
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
				</div>
				<div class="elementor-element elementor-element-574b1c9 elementor-widget elementor-widget-text-editor" data-id="574b1c9" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
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									<p>The course will begin with an analysis of the hypothesis test, a statistical test used to compare two data sets for the purpose of rejecting a null hypothesis and not to indicate the more likely of two hypotheses. The students will also be introduced in the process of randomization, of making something random, for example on how to select a random sample of a population. In addition, the course will provide detailed information on some of the most commonly used distributions and an analysis of the central limit theorem which establishes that the sum of independent random variables tends toward a normal distribution although the original variables may not. Time will be allocated in the presentation of parametric and nonparametric tests and their comparison in order for the students to understand the prerequisites for applying one or the other. Special attention will be given to the multiple comparison problems and means to overcome it. The problem arises from the fact that when you are performing multiple statistical tests a fraction of them is false positives. The application of Linear, Logistic and Cox models will be also presented.</p>								</div>
				</div>
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															<img fetchpriority="high" decoding="async" width="1024" height="770" src="https://masterneuroscience.gr/wp-content/uploads/2024/02/a.svg" class="attachment-large size-large wp-image-13114" alt="" />															</div>
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Technical Courses I: Methodological approaches in Neuroscience, Statistics (SPSS, R programming, graphpad)</h2>				</div>
				</div>
					</div>
		</div>
					</div>
		</section>
				<section class="elementor-section elementor-top-section elementor-element elementor-element-1f4a7f6 elementor-section-boxed elementor-section-height-default elementor-section-height-default qodef-elementor-content-no" data-id="1f4a7f6" data-element_type="section" data-e-type="section">
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
				</div>
				<div class="elementor-element elementor-element-b6fc493 elementor-widget elementor-widget-text-editor" data-id="b6fc493" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
				<div class="elementor-widget-container">
									<p>This course is intended to cover the basic statistical principles usually applied in the biological sciences. The goal of the course is to provide the students with the ability to choose and apply the appropriate statistics for their studies.</p>								</div>
				</div>
		<div class="elementor-element elementor-element-c3a77b8 e-flex e-con-boxed e-con e-child" data-id="c3a77b8" data-element_type="container" data-e-type="container">
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				<div class="elementor-element elementor-element-9782e80 elementor-widget elementor-widget-heading" data-id="9782e80" data-element_type="widget" data-e-type="widget" data-widget_type="heading.default">
				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
				</div>
				<div class="elementor-element elementor-element-690bc83 elementor-widget elementor-widget-text-editor" data-id="690bc83" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
				<div class="elementor-widget-container">
									<p>The course will begin with an analysis of the hypothesis test, a statistical test used to compare two data sets for the purpose of rejecting a null hypothesis and not to indicate the more likely of two hypotheses. The students will also be introduced in the process of randomization, of making something random, for example on how to select a random sample of a population. In addition, the course will provide detailed information on some of the most commonly used distributions and an analysis of the central limit theorem which establishes that the sum of independent random variables tends toward a normal distribution although the original variables may not. Time will be allocated in the presentation of parametric and nonparametric tests and their comparison in order for the students to understand the prerequisites for applying one or the other. Special attention will be given to the multiple comparison problems and means to overcome it. The problem arises from the fact that when you are performing multiple statistical tests a fraction of them is false positives. The application of Linear, Logistic and Cox models will be also presented.</p>								</div>
				</div>
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															<img decoding="async" width="1024" height="1004" src="https://masterneuroscience.gr/wp-content/uploads/2024/02/b.svg" class="attachment-large size-large wp-image-13115" alt="" />															</div>
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Technical courses II: Molecular Biology-Omics</h2>				</div>
				</div>
					</div>
		</div>
					</div>
		</section>
				<section class="elementor-section elementor-top-section elementor-element elementor-element-e2c64b9 elementor-section-boxed elementor-section-height-default elementor-section-height-default qodef-elementor-content-no" data-id="e2c64b9" data-element_type="section" data-e-type="section">
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					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
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									<p>These series of lectures will provide</p>								</div>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.8125 48.4688V55H4.03125V48.4688H14.9375V18.4375L4.375 25.0312V18.125L15.4062 10.9688H23.7188V48.4688H33.8125Z" fill="#092640"></path><path d="M49 45.4688V55H39.9688V45.4688H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">an overview of Next Generation Sequencing (NGS) and the most relevant biomedical NGS applications: Targeted sequencing, Whole-exome sequencing, Whole-genome sequencing, RNA-seq (mRNA-seq, smallRNA-seq, etc., approaches to study RNA structure and RNA-protein interactions), approaches to interrogate the composition and structure of chromatin (ChIP-seq, ATAC-seq, chromosome conformation capture techniques, etc.). </span>
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										<span class="elementor-icon-list-text">an introduction to proteomic methodologies and their application to the study of human diseases. </span>
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										<span class="elementor-icon-list-text">an introduction of the significance but also the challenges of applying metabolomic analysis in neurophysiology research. The students will be presented with the major changes in the way problems in life sciences are now approached in the context of the systems biology and the omic analyses revolution, focusing on brain research and the field of systems neurophysiology. The muti-step metabolomic analysis will be described and its contribution to the reconstruction of an accurate metabolic physiology map for the brain will be discussed. Experimental and computational protocol standardization challenges that need to be addressed for its vast deployment in neurophysiology research and practice will be described. An example of brain metabolomic analysis in a mouse model will be presented.</span>
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										<span class="elementor-icon-list-text">Examples of genetic and biochemical approaches to develop agents interfering with protein aggregation. Many neurodegenerative diseases are associated with protein misfolding and protein self-assembly, which lead to the formation of protein oligomers and/or higher-order aggregates with neurotoxic properties. Thus, understanding these pathogenic processes is of fundamental importance for neurobiology. Furthermore, chemical and biological agents interfering with protein aggregation are much sought-after factors in the quest for effective drugs against these conditions.</span>
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					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
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									<p>The course will cover basic principles of NGS technologies, description of the omic analysis revolution and the consequent fundamental changes in the way problems in life sciences are now approached, mass spectrometry and applications involving differential proteomics, identification of post-translational modifications and analysis of protein complexes as well as of metabolomics. Description of the multi-step experimental and computational analysis process that needs to be carefully designed and standardized for its accurate and vast application in neurophysiology research.</p><p>Furthermore, biochemical, biophysical and biological assays, which can be utilized for high-throughput screenings of chemical and biological libraries so as to discover modulators of protein aggregation will be described. Furthermore, the design, development and outcomes of recently developed biotechnological platforms for producing chemical libraries with greatly expanded diversities and for identifying chemical rescuers of pathogenic protein misfolding and aggregation in an ultrahigh-throughput fashion will also be covered. </p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Skills &amp; Learning Outcomes</h2>				</div>
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									<p>The objective will be to familiarize students with</p>								</div>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.8125 48.4688V55H4.03125V48.4688H14.9375V18.4375L4.375 25.0312V18.125L15.4062 10.9688H23.7188V48.4688H33.8125Z" fill="#092640"></path><path d="M49 45.4688V55H39.9688V45.4688H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">the principles underlying NGS and the main biomedical applications in which NGS is employed</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.0312 47.7715V54.9902H2.21875V48.8965C2.98958 47.209 3.96875 45.5632 5.15625 43.959C6.34375 42.334 7.76042 40.709 9.40625 39.084C11.0729 37.4382 12.9688 35.7507 15.0938 34.0215C16.6354 32.7715 17.9479 31.6361 19.0312 30.6152C20.1146 29.5736 20.9583 28.6465 21.5625 27.834C22.1875 27.0215 22.6562 26.2194 22.9688 25.4277C23.2812 24.6152 23.4375 23.8236 23.4375 23.0527C23.4375 21.1361 22.9479 19.6986 21.9688 18.7402C21.0104 17.7819 19.5729 17.3027 17.6562 17.3027C15.7812 17.3027 14.3438 17.8132 13.3438 18.834C12.3646 19.834 11.7292 21.3444 11.4375 23.3652L2.59375 22.8652C3.09375 18.7819 4.61458 15.6673 7.15625 13.5215C9.71875 11.3757 13.1979 10.3027 17.5938 10.3027C22.3438 10.3027 25.9896 11.3861 28.5312 13.5527C31.0729 15.7194 32.3438 18.7611 32.3438 22.6777C32.3438 24.8861 31.8854 26.8652 30.9688 28.6152C30.0521 30.3652 28.8854 31.9798 27.4688 33.459C26.3021 34.7298 24.9792 35.9382 23.5 37.084C22.0417 38.2298 20.625 39.3444 19.25 40.4277C17.7917 41.5944 16.4583 42.7715 15.25 43.959C14.0625 45.1465 13.1771 46.4173 12.5938 47.7715H33.0312Z" fill="#092640"></path><path d="M49 45.459V54.9902H39.9688V45.459H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">the experimental design of proteomic experiments and current challenges in their application to the study of human diseases</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.2812 42.7812C33.2812 46.9062 31.9271 50.0938 29.2188 52.3438C26.5104 54.5938 22.6562 55.7188 17.6562 55.7188C12.9271 55.7188 9.16667 54.6354 6.375 52.4688C3.58333 50.2812 1.94792 47.1354 1.46875 43.0312L10.4062 42.25C10.9688 46.4792 13.375 48.5938 17.625 48.5938C19.7292 48.5938 21.3646 48.0729 22.5312 47.0312C23.6979 45.9896 24.2812 44.3958 24.2812 42.25C24.2812 40.2917 23.5729 38.7917 22.1562 37.75C20.7396 36.7083 18.6354 36.1875 15.8438 36.1875H12.7812V29.0938H15.6562C18.1771 29.0938 20.0729 28.5833 21.3438 27.5625C22.6146 26.5208 23.25 25.0417 23.25 23.125C23.25 21.3125 22.7396 19.8958 21.7188 18.875C20.7188 17.8333 19.25 17.3125 17.3125 17.3125C15.5 17.3125 14.0312 17.8125 12.9062 18.8125C11.8021 19.8125 11.1667 21.2292 11 23.0625L2.21875 22.4375C2.67708 18.6458 4.25 15.6771 6.9375 13.5312C9.625 11.3854 13.1354 10.3125 17.4688 10.3125C22.0729 10.3125 25.6667 11.3542 28.25 13.4375C30.8542 15.5 32.1562 18.3646 32.1562 22.0312C32.1562 24.7812 31.3438 27.0417 29.7188 28.8125C28.1146 30.5833 25.7917 31.7604 22.75 32.3438V32.4688C26.125 32.8646 28.7188 33.9792 30.5312 35.8125C32.3646 37.625 33.2812 39.9479 33.2812 42.7812Z" fill="#092640"></path><path d="M49 45.4688V55H39.9688V45.4688H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">the holistic perspective of biological system analysis gained from systems and network biology research and shown the complementary role of the various omic analyses in deciphering the complexity of brain function</span>
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										<span class="elementor-icon-list-text">metabolomic analysis and it’s various experimental and computational components</span>
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										<span class="elementor-icon-list-text">network reconstruction and how this could contribute to the elucidation of brain metabolic physiology and the reconstruction of the entire brain connectome</span>
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										<span class="elementor-icon-list-text">the experimental and computational challenges that need to be considered for accurate application of metabolomics in brain research</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="47" height="45" viewBox="0 0 47 45" fill="none"><path d="M30.7812 7.9375C28.8021 11.0625 26.9271 14.0938 25.1562 17.0312C23.4062 19.9479 21.875 22.8958 20.5625 25.875C19.25 28.8333 18.2083 31.8854 17.4375 35.0312C16.6875 38.1771 16.3125 41.5 16.3125 45H7.15625C7.15625 41.6458 7.52083 38.4688 8.25 35.4688C8.97917 32.4479 10.1354 29.2708 11.7188 25.9375C12.7604 23.7708 14.1354 21.2917 15.8438 18.5C17.5521 15.7083 19.8125 12.2708 22.625 8.1875H0.75V0.96875H30.7812V7.9375Z" fill="#092640"></path><path d="M47 35.4688V45H37.9688V35.4688H47Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">state-of-the-art high-throughput approaches for monitoring neurodegeneration-associated protein aggregation and for identifying chemical and biological inhibitors of these processes</span>
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										<span class="elementor-icon-list-text">recently developed biotechnological approaches for the discovery of chemical rescuers of protein misfolding and aggregation with potentially therapeutic effects against major neurodegenerative diseases</span>
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					<h2 class="elementor-heading-title elementor-size-default">Technical courses III: Methodological approaches in Neuroscience, Elements of Bioinformatics (big data bases)</h2>				</div>
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					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
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									<p>This is an intensive two and a half week course focused on computational analysis and robust interpretation of molecular data streams, generated by a broad spectrum of high-throughput experimental technologies, termed as -omics.  Overall these technologies revolutionize the landscape of modern biological research, enabling adoption of holistic approaches in the study and modification of biological mechanisms, yet their efficient integration in the discovery cycle entails great challenges, due to their immense complexity. The derivation of the instrumental molecular networks, behind disease emergence and progression, requests the intelligent utilization of powerful, computational strategies, in order to single out of the millions of biological measurements, those pivotal for the disease interrogated. Moreover, it is crucial to prioritize the important cellular events, in order to be able to propose a rational, combinatorial therapeutic approach, targeting these events, with novel combinations of compounds. In this direction, the various pillars of computational analysis that aid efficient and robust integration, analysis and interpretation of high-dimensional, omic data, potentially from multiple layers of dissection (cross-omics) will be examined, as well as the respective experimental technologies they support.</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
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									<p>Ultimate goal of this intensive course is that students are gaining familiarization with this broad pool of experimental technologies, under the umbrella of -omics, together with the various sorts of bio-informatic analytical algorithms and workflows, deployed at different stages and for different data-types. In addition, emphasis will be given in the meaningful integration and robust functional interpretation, in terms of the active emergent molecular modules that shape the phenotypic landscape of the biological problem interrogated, as well as the reliable association of molecular with phenotypic markers. The course will review the application of these concepts in the field of epidemiological stratification, pharmacogenomics analysis and personalized medicine. </p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Topics to be discussed will cover</h2>				</div>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Next generation sequencing technologies, providing an introduction coupled by an overview of the main Next Generation sequencing methodologies (Gen-Seq, Exome seq, RNA- Seq, ChIP-Seq, etc), from the point of view of the computational analysis (de-novo / Reference Genome-based Assembly, Filtering, Signal Estimation, Differential Expression, Statistical Selection, Variant Calling)  </span>
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											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Microarray technologies and their processing (background correction, signal estimation, normalization, filtering and statistical selection) </span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Bioinformatic methodologies for multi-layered structural and functional characterization  of nucleotide and aminoacid sequences (homology based screening, ORF and gene function prediction, taxonomic and phylogenetic analysis, protein domain analysis, machine learning for functional characterization of proteins, regulatory motif analysis, hot-spot prediction, metagenomic screening) </span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Translational, integrative bioinfomatic analysis of omic datasets, which highlight the critical biological processes implicated in the biological problem interrogated (integrative methodologies, enrichment statistics, ontologies and controlled vocabularies, resampling based correction, gene set analysis, pathway prioritization, pharmacogenomic  knowledgebases) </span>
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										<span class="elementor-icon-list-text">Target prioritization and diagnostic stratification discussing the methodologies for the inference of small-sized, highly informative signatures for diagnostic classification, pharmacogenomic analysis, combinatorial treatment (semantic networks, interaction networks, network inference and analysis, derivation of molecular signatures, classification and clustering methodologies, machine learning techiques) </span>
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					<h2 class="elementor-heading-title elementor-size-default">Skills &amp; Learning Outcomes</h2>				</div>
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									<p>Upon successful completion of this course, students will be able to define, describe and discern critical functional features of:</p>								</div>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.8125 48.4688V55H4.03125V48.4688H14.9375V18.4375L4.375 25.0312V18.125L15.4062 10.9688H23.7188V48.4688H33.8125Z" fill="#092640"></path><path d="M49 45.4688V55H39.9688V45.4688H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">the main Next Generation Sequencing Methodologies and their fundamental computational steps. </span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.0312 47.7715V54.9902H2.21875V48.8965C2.98958 47.209 3.96875 45.5632 5.15625 43.959C6.34375 42.334 7.76042 40.709 9.40625 39.084C11.0729 37.4382 12.9688 35.7507 15.0938 34.0215C16.6354 32.7715 17.9479 31.6361 19.0312 30.6152C20.1146 29.5736 20.9583 28.6465 21.5625 27.834C22.1875 27.0215 22.6562 26.2194 22.9688 25.4277C23.2812 24.6152 23.4375 23.8236 23.4375 23.0527C23.4375 21.1361 22.9479 19.6986 21.9688 18.7402C21.0104 17.7819 19.5729 17.3027 17.6562 17.3027C15.7812 17.3027 14.3438 17.8132 13.3438 18.834C12.3646 19.834 11.7292 21.3444 11.4375 23.3652L2.59375 22.8652C3.09375 18.7819 4.61458 15.6673 7.15625 13.5215C9.71875 11.3757 13.1979 10.3027 17.5938 10.3027C22.3438 10.3027 25.9896 11.3861 28.5312 13.5527C31.0729 15.7194 32.3438 18.7611 32.3438 22.6777C32.3438 24.8861 31.8854 26.8652 30.9688 28.6152C30.0521 30.3652 28.8854 31.9798 27.4688 33.459C26.3021 34.7298 24.9792 35.9382 23.5 37.084C22.0417 38.2298 20.625 39.3444 19.25 40.4277C17.7917 41.5944 16.4583 42.7715 15.25 43.959C14.0625 45.1465 13.1771 46.4173 12.5938 47.7715H33.0312Z" fill="#092640"></path><path d="M49 45.459V54.9902H39.9688V45.459H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">the current state-of-the-art microarray technologies, popular platform configurations for various omic experimental designs, and the requisite algorithmic processing steps. </span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M33.2812 42.7812C33.2812 46.9062 31.9271 50.0938 29.2188 52.3438C26.5104 54.5938 22.6562 55.7188 17.6562 55.7188C12.9271 55.7188 9.16667 54.6354 6.375 52.4688C3.58333 50.2812 1.94792 47.1354 1.46875 43.0312L10.4062 42.25C10.9688 46.4792 13.375 48.5938 17.625 48.5938C19.7292 48.5938 21.3646 48.0729 22.5312 47.0312C23.6979 45.9896 24.2812 44.3958 24.2812 42.25C24.2812 40.2917 23.5729 38.7917 22.1562 37.75C20.7396 36.7083 18.6354 36.1875 15.8438 36.1875H12.7812V29.0938H15.6562C18.1771 29.0938 20.0729 28.5833 21.3438 27.5625C22.6146 26.5208 23.25 25.0417 23.25 23.125C23.25 21.3125 22.7396 19.8958 21.7188 18.875C20.7188 17.8333 19.25 17.3125 17.3125 17.3125C15.5 17.3125 14.0312 17.8125 12.9062 18.8125C11.8021 19.8125 11.1667 21.2292 11 23.0625L2.21875 22.4375C2.67708 18.6458 4.25 15.6771 6.9375 13.5312C9.625 11.3854 13.1354 10.3125 17.4688 10.3125C22.0729 10.3125 25.6667 11.3542 28.25 13.4375C30.8542 15.5 32.1562 18.3646 32.1562 22.0312C32.1562 24.7812 31.3438 27.0417 29.7188 28.8125C28.1146 30.5833 25.7917 31.7604 22.75 32.3438V32.4688C26.125 32.8646 28.7188 33.9792 30.5312 35.8125C32.3646 37.625 33.2812 39.9479 33.2812 42.7812Z" fill="#092640"></path><path d="M49 45.4688V55H39.9688V45.4688H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">the main structural bioinformatic algorithmic tools that are available for the analysis and functional characterization of nucleotide and aminoacid sequences. </span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="54" height="65" viewBox="0 0 54 65" fill="none"><path d="M29.375 46.0312V55H21V46.0312H0.96875V39.4375L19.5625 10.9688H29.375V39.5H35.25V46.0312H29.375ZM8.125 39.5H21V25.0938C21 23.9688 21.0312 22.75 21.0938 21.4375C21.1771 20.125 21.2396 19.2812 21.2812 18.9062C21.0104 19.4896 20.625 20.2083 20.125 21.0625C19.6458 21.8958 19.0521 22.8646 18.3438 23.9688L8.125 39.5Z" fill="#092640"></path><path d="M49 45.4688V55H39.9688V45.4688H49Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">various molecular enrichment, gene set and pathway analysis tools / platforms.</span>
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										<span class="elementor-icon-list-text">Network based methodologies for target prioritization, connectivity with drug-related databases, geometric estimation of complexity (Principal Component Analysis) supervised (machine learning, Linear discriminant analysis, PLS) and unsupervised (clustering) classification of phenotypic categories</span>
									</li>
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					<h2 class="elementor-heading-title elementor-size-default">Titles of lectures and names of the lecturers</h2>				</div>
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									<table width="553"><tbody><tr><td width="87"><p><strong>A/A</strong></p></td><td width="349"><p><strong>TECHNICAL COURSES: Statistics, Molecular Biology, Bioinformatics</strong></p></td><td width="116"><p><strong>Lecturers</strong></p></td></tr><tr><td width="87"><p>1</p></td><td width="349"><p>Comparing means, one- and two- sample tests (parametric and non-parametric), ANOVA, Confounding variables: presence and control of confounding effects</p></td><td width="116"><p><strong>Nikos Fyllas</strong></p></td></tr><tr><td width="87"><p>2</p></td><td width="349"><p>Correlational designs, Correlation and Regression, Multiple Linear Regression</p></td><td width="116"><p><strong>Nikos Fyllas</strong></p></td></tr><tr><td width="87"><p>3</p></td><td width="349"><p>Random variables and Probability Distributions, Descriptive statistics, Framing and Testing Hypotheses, Meaning of statistical significance, R overview</p></td><td width="116"><p><strong>Nikos Fyllas</strong></p></td></tr><tr><td width="87"><p>4</p></td><td width="349"><p>High throughput assays-amyloid disassembly or prevention of protein aggregation</p></td><td width="116"><p><strong>George Skretas</strong></p></td></tr><tr><td width="87"><p>5</p></td><td width="349"><p>Next Generation Sequencing and its applications in Biomedicine. Genomics</p></td><td width="116"><p><strong>Pantelis Hatzis</strong></p></td></tr><tr><td width="87"><p>6</p></td><td width="349"><p>Next Generation Sequencing and its applications in Biomedicine. Genomics</p></td><td width="116"><p><strong>Pantelis Hatzis</strong></p></td></tr><tr><td width="87"><p>7</p></td><td width="349"><p>Next Generation Sequencing and its applications in Biomedicine. Genomics</p></td><td width="116"><p><strong>Pantelis Hatzis</strong></p></td></tr><tr><td width="87"><p>8</p></td><td width="349"><p>Proteomics</p></td><td width="116"><p><strong>George Panayotou</strong></p></td></tr><tr><td width="87"><p>9</p></td><td width="349"><p>Data Analysis and Results Visualization in Proteomics</p></td><td width="116"><p><strong>Martina Samiotaki</strong></p></td></tr><tr><td width="87"><p>10</p></td><td width="349"><p>Introduction to Bioinformatics, Biological Data Types, Biological Repositories, Querying Biological Databases, sequence analysis, sequence-structure-function, taxonomic/phylogenetic analysis</p></td><td width="116"><p><strong>E. Pilalis</strong><strong>-Fani Gkotsi</strong></p></td></tr><tr><td width="87"><p>11</p></td><td width="349"><p>Analysis of Biological signals (Microarrays/ Next Generation Seq technologies), types of biological signals and workflows, processing steps</p></td><td width="116"><p><strong>E. Pilalis</strong><strong>-Fani Gkotsi</strong></p></td></tr><tr><td width="87"><p>12</p></td><td width="349"><p>Signature mediated interpretation, stratification, machine learning, precision medicine</p></td><td width="116"><p><strong>E. Pilalis</strong><strong>-Fani Gkotsi</strong></p></td></tr><tr><td width="87"><p>13</p></td><td width="349"><p>Protein and DNA Sequence Analysis</p></td><td width="116"><p><strong>I. Michalopoulos</strong></p></td></tr></tbody></table>								</div>
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		<title>Developmental Neuroscience</title>
		<link>https://masterneuroscience.gr/course/developmental-neuroscience/</link>
		
		<dc:creator><![CDATA[dmhsupport]]></dc:creator>
		<pubDate>Wed, 03 Jan 2024 10:27:01 +0000</pubDate>
				<guid isPermaLink="false">https://masterneuroscience.gr/?post_type=course&#038;p=10475</guid>

					<description><![CDATA[Teaching hours and weekly schedule This is a 1st semester course of about 2.5 weeks that corresponds to 5 ECTs and 39 hours of lectures including student presentations. The course will take place in October-November and the weekly schedule includes about 4 hours of teaching per day every afternoon. Co-ordinators &#160; Rebecca Matsas, Research Director,&#8230; <a class="continue" href="https://masterneuroscience.gr/course/developmental-neuroscience/">Continue Reading<span> Developmental Neuroscience</span></a>]]></description>
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									<p>This is a 1st semester course of about 2.5 weeks that corresponds to 5 ECTs and 39 hours of lectures including student presentations.<br />The course will take place in October-November and the weekly schedule includes about 4 hours of teaching per day every afternoon.</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Co-ordinators</h2>				</div>
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										<span class="elementor-icon-list-text">Rebecca Matsas, Research Director, Head of Department of Neurobiology, Hellenic Pasteur Institute</span>
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										<span class="elementor-icon-list-text">Panagiotis Politis, Principal Investigator, Biomedical Research Foundation of the Academy of Athens</span>
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					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
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									<p>This is an intensive 2.5-week course focused on cellular, molecular and biochemical aspects of developmental neurobiology and neuroscience. The courses will include lectures by established researchers with diverse and complementary academic profiles. The main emphasis of the course will be on the complex cellular events and signaling cascades that occur during embryogenesis that lead to generation of the nervous system. Our goal is to provide a systematic introduction to the molecular mechanisms that control cell fate specification, differentiation, and function of neural cells during mammalian brain development. An additional aim is to discuss nervous system plasticity in the adult brain and particularly how the presence of adult neural stem cells may contribute to brain repair strategies. Special attention will be given to describe the key methodological advances and research tools, developed in the last few years, which have changed our view about the formation of the mammalian brain. Therefore, this course will provide a contemporary overview of neural development for post-graduate students with some background in cell biology.</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
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									<div><p><span style="font-weight: 400;">This course aims: a) to introduce participants to the major issues of developmental neuroscience, b) to familiarize students with the wide range of research approaches, tools and methodology currently used to study the development of the mammalian nervous system, c) to discuss the concept of neural stem cells during development and in the adult and d) to encourage students to develop the skills required for a meaningful appreciation of experimental strategies and research articles.</span></p><p><span style="font-weight: 400;">This course will cover recent advances in understanding the molecular and cellular events underlying cell fate specification and differentiation, migration, axon guidance, synapse formation, the critical role of neurotrophic factors, and cell death as a developmental process. Pathologies arising from failures of these processes will be discussed. In particular, the lectures will cover the following general subjects:</span></p></div>								</div>
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										<span class="elementor-icon-list-text">Neural Induction                 </span>
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										<span class="elementor-icon-list-text">Neural tube formation and patterning</span>
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										<span class="elementor-icon-list-text">Cortical &amp; Cerebellar Neurogenesis</span>
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										<span class="elementor-icon-list-text">Regulatory mechanisms of cell cycle progression/exit</span>
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										<span class="elementor-icon-list-text">Neuronal migration and differentiation</span>
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										<span class="elementor-icon-list-text">Axon Guidance &amp; Adhesion Molecules</span>
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										<span class="elementor-icon-list-text">Synapses: formation, function and plasticity</span>
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										<span class="elementor-icon-list-text">Development of neural circuits</span>
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										<span class="elementor-icon-list-text">Development of the neuroimmune system</span>
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										<span class="elementor-icon-list-text">Gliogenesis, myelination, remyelination</span>
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										<span class="elementor-icon-list-text">Neural stem cells, adult neurogenesis &amp; neuroregeneration</span>
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										<span class="elementor-icon-list-text">Advanced Methods in Developmental &amp; Regenerative Neurobiology</span>
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					<h2 class="elementor-heading-title elementor-size-default">Titles of lectures and names of the lecturers</h2>				</div>
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									<table width="542"><tbody><tr><td width="47"><p><strong>A/A</strong></p></td><td width="344"><p><strong>Developmental Neuroscience</strong></p></td><td width="151"><p><strong>Lecturer</strong></p></td></tr><tr><td width="47"><p>1</p></td><td width="344"><p>Neural Induction / Neural tube formation and patterning</p></td><td width="151"><p>Panos Politis</p></td></tr><tr><td width="47"><p>2</p></td><td width="344"><p>Cortical Neurogenesis</p></td><td width="151"><p>Myrto Denaxa</p></td></tr><tr><td width="47"><p>3</p></td><td width="344"><p>Cerebellar Neurogenesis, Adult Neurogenesis, Modeling human brain development and disease “in a dish</p></td><td width="151"><p>Rebecca Matsas</p></td></tr><tr><td width="47"><p>4</p></td><td width="344"><p>Gliogenesis &amp; myelination</p></td><td width="151"><p>Florentia Papastefanaki</p></td></tr><tr><td width="47"><p>5</p></td><td width="344"><p>Axon Guidance &amp; Adhesion Molecules</p></td><td width="151"><p>Maria Gaitanou</p></td></tr><tr><td width="47"><p>6</p></td><td width="344"><p>Development of neural</p><p>circuits and plasticity</p></td><td width="151"><p>Laskaro Zagoraiou</p></td></tr><tr><td width="47"><p>7</p></td><td width="344"><p>Synapse: formation and</p><p>function</p></td><td width="151"><p>Nondas Doxakis</p></td></tr><tr><td width="47"><p>8</p></td><td width="344"><p>Development of the neuroimmune system</p></td><td width="151"><p>Era Taoufik</p></td></tr><tr><td width="47"><p>9</p></td><td width="344"><p>Trophic factors and programmed cell death during nervous system development</p></td><td width="151"><p>Giannis</p><p>Charalampopoulos</p></td></tr><tr><td width="47"><p>10</p></td><td width="344"><p>Advanced methods in developmental &amp; regenerative neurobiology</p></td><td width="151"><p>Myrto Denaxa</p></td></tr><tr><td width="47"><p>11</p></td><td width="344"><p>Environmental and hormonal regulation of neurodevelopment</p></td><td width="151"><p>Giasemi Koutmani</p></td></tr><tr><td width="47"><p>12</p></td><td width="344"><p>Evolutionary perspectives of human cortical development</p></td><td width="151"><p>Christina Kyrousi</p></td></tr></tbody></table>								</div>
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		<title>Cellular and Molecular Neuroscience</title>
		<link>https://masterneuroscience.gr/course/cellular-molecular-neuroscience/</link>
		
		<dc:creator><![CDATA[dmhsupport]]></dc:creator>
		<pubDate>Tue, 02 Jan 2024 10:27:12 +0000</pubDate>
				<guid isPermaLink="false">https://masterneuroscience.gr/?post_type=course&#038;p=10476</guid>

					<description><![CDATA[Teaching hours and weekly schedule Teaching hours and weekly schedule. This is a 1st semester course of about 2.5 weeks that corresponds to 5 ECTs and 39 total hours of lectures including student presentations. Co-ordinators &#160; Dimitra Mangoura, Professor-Investigator A, Biomedical Research Foundation of the Academy of Athens Zafiroula–Iro Georgoussi, Research Director, National Center for&#8230; <a class="continue" href="https://masterneuroscience.gr/course/cellular-molecular-neuroscience/">Continue Reading<span> Cellular and Molecular Neuroscience</span></a>]]></description>
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									<p>Teaching hours and weekly schedule. This is a 1st semester course of about 2.5 weeks that corresponds to 5 ECTs and 39 total hours of lectures including student presentations.</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Co-ordinators</h2>				</div>
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										<span class="elementor-icon-list-text">Dimitra Mangoura, Professor-Investigator A, Biomedical Research Foundation of the Academy of Athens</span>
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										<span class="elementor-icon-list-text">Zafiroula–Iro Georgoussi, Research Director, National Center for Scientific Research “Demokritos”, Athens</span>
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					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
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									<p>This course is designed to introduce graduate students to major processes, principles, and mechanisms associated with Cellular and Molecular Neurobiology. Therefore the material will range from the mechanistic details of neuronal signaling and cellular function to how such properties utilized during normal brain function and neuropathology or substance abuse. The Course involves a series of overview lectures by leading researchers in the field, a total of fifteen Instructors from Greece and across Europe, and opportunities of presenting primary research or literature review papers by students.<br />More specifically, this Course will include the following major topics: overview of the neuron as the fundamental unit; cell biology of neurons and glia; ion channels and electrical signaling; synaptic transmission, integration, and chemical systems of the brain; molecular properties of neurotransmitters and their receptors; and sensory systems, from transduction to perception. Students will emerge with a great awareness of how individual nerve cells function, and neurons communicate with other cells, and of the ways that neurotransmission can provide insight into basic scientific questions, all in preparation for students own contributions as neuroscientists and biologists.</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
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									<p>This is a comprehensive introductory course in Molecular and Cellular Neuroscience. Basic principles of organization and function of the nervous system will be discussed and frequent reference will be made to pathophysiology of neurological and other disorders.</p>								</div>
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										<span class="elementor-icon-list-text">General principles of Nervous System              </span>
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										<span class="elementor-icon-list-text">Synaptic Transmission, Neurotransmitters and their Receptors</span>
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										<span class="elementor-icon-list-text">Molecular Aspects of Neuronal Cells</span>
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					<h2 class="elementor-heading-title elementor-size-default">Skills &amp; Learning Outcomes</h2>				</div>
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									<p>Upon successful completion of this course, students will be able to know the fundamental principles on:</p>								</div>
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										<span class="elementor-icon-list-text">Neural cell biology</span>
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										<span class="elementor-icon-list-text">Synapse formation and neural plasticity</span>
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										<span class="elementor-icon-list-text">Intracellular trafficking and cytoskeleton-related processes</span>
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										<span class="elementor-icon-list-text">Interconnections to form nerve circuits for the passage of electric signals</span>
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										<span class="elementor-icon-list-text">Small molecules coupling to their cognate membrane receptors to regulate intracellular responses and biological outcomes</span>
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										<span class="elementor-icon-list-text">Major intracellular signalling pathways</span>
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										<span class="elementor-icon-list-text">Molecular biology of the sensory systems</span>
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										<span class="elementor-icon-list-text">Energy brain metabolism</span>
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										<span class="elementor-icon-list-text">Titles of lectures and names of the lecturers</span>
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									<table style="height: 1262px;" width="626"><tbody><tr><td width="48"><p><strong>A/A</strong></p></td><td width="335"><p><strong>Cellular and Molecular Neurobiology</strong></p></td><td width="187"><p><strong>Lecturer</strong></p></td></tr><tr><td width="48"><p>1</p></td><td width="335"><p>Overview of the Nervous System</p></td><td width="187"><p>Mimika Mangoura</p></td></tr><tr><td width="48"><p>2</p></td><td width="335"><p>Cell Membrane Structures and Functions</p></td><td width="187"><p>Mimika Mangoura</p></td></tr><tr><td width="48"><p>3</p></td><td width="335"><p>The cytoskeleton of neural cells</p></td><td width="187"><p>Mimika Mangoura</p></td></tr><tr><td width="48"><p>4</p></td><td width="335"><p>Intracellular Trafficking</p></td><td width="187"><p>Mimika Mangoura</p></td></tr><tr><td width="48"><p>5</p></td><td width="335"><p>Axonal transport</p></td><td width="187"><p>Mimika Mangoura</p></td></tr><tr><td width="48"><p>6</p></td><td width="335"><p>Protein synthesis and posttranslational modifications</p></td><td width="187"><p>Mimika Mangoura</p></td></tr><tr><td width="48"> </td><td width="335"><p><strong>Synaptic Transmission and Signalling</strong></p></td><td width="187"> </td></tr><tr><td width="48"><p>7</p></td><td width="335"><p>Neurotransmitters, Receptors, G proteins</p></td><td width="187"><p>Iro Georgoussi</p></td></tr><tr><td width="48"><p>8</p></td><td width="335"><p>Effectors, signaling intermediates, drug design</p></td><td width="187"><p>Iro Georgoussi</p></td></tr><tr><td width="48"><p>9</p></td><td width="335"><p>Neurobiology of addiction</p></td><td width="187"><p>Katia Befort, France</p></td></tr><tr><td width="48"><p>10</p></td><td width="335"><p>Neurotransmitters II: Gas neurotransmitters</p></td><td width="187"><p>Spiros Efthimiopoulos</p></td></tr><tr><td width="48"><p>11</p></td><td width="335"><p>Neurotransmitters I: Cannabinoid receptors</p></td><td width="187"><p>Ismael Galve-Roperh, Spain</p></td></tr><tr><td width="48"><p>12</p></td><td width="335"><p>Phosphoinositides</p></td><td width="187"><p>George Leondaritis</p></td></tr><tr><td width="48"><p>12</p></td><td width="335"><p>Neurotransmitters III: GABA</p></td><td width="187"><p>Haralambos Lambrakakis</p></td></tr><tr><td width="48"><p>12</p></td><td width="335"><p>Neurotransmitters V: Peptide neurotransmitters</p></td><td width="187"><p>Iro Georgoussi</p></td></tr><tr><td width="48"><p>13</p></td><td width="335"><p>Neurotransmitters IV: Acetylcholine</p></td><td width="187"><p>Marios Zouridakis</p></td></tr><tr><td width="48"><p> 13</p></td><td width="335"><p>Neurotransmitters V: Glutamate</p></td><td width="187"><p>Kostas Pallikaras</p></td></tr><tr><td width="48"><p>17</p></td><td width="335"><p>Neurotransmitters VI: Catecholamines</p></td><td width="187"><p>Kostas Vekrellis</p></td></tr><tr><td width="48"><p>17</p></td><td width="335"><p>Ca2+ signaling and Homeostasis</p></td><td width="187"><p>Panagiota Papazafiri</p></td></tr></tbody></table>								</div>
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		<title>Neurophysiology</title>
		<link>https://masterneuroscience.gr/course/neurophysiology/</link>
		
		<dc:creator><![CDATA[dmhsupport]]></dc:creator>
		<pubDate>Tue, 21 Nov 2023 14:23:59 +0000</pubDate>
				<guid isPermaLink="false">https://masterneuroscience.gr/?post_type=course&#038;p=10465</guid>

					<description><![CDATA[Teaching hours and weekly schedule This is a 1st semester elective course of about 2,5 weeks that corresponds to 5 ECTs and 39 total hours of lectures including student presentations.. Co-ordinators &#160; Irene Skaliora, Professor of Neuroscience and Cognitive Science, Department of History and Philosophy of Science, National &#38; Kapodistrian University of Athens and Biomedical&#8230; <a class="continue" href="https://masterneuroscience.gr/course/neurophysiology/">Continue Reading<span> Neurophysiology</span></a>]]></description>
										<content:encoded><![CDATA[		<div data-elementor-type="wp-post" data-elementor-id="10465" class="elementor elementor-10465" data-elementor-post-type="course">
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					<h2 class="elementor-heading-title elementor-size-default">Teaching hours and weekly schedule</h2>				</div>
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									<p>This is a 1st semester elective course of about 2,5 weeks that corresponds to 5 ECTs and 39 total hours of lectures including student presentations..</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Co-ordinators</h2>				</div>
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										<span class="elementor-icon-list-text">Irene Skaliora, Professor of Neuroscience and Cognitive Science, Department of History and Philosophy of Science, National &amp; Kapodistrian University of Athens and Biomedical Research Foundation of the Academy of Athens.</span>
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										<span class="elementor-icon-list-text">Christos Consoulas, Associate Professor of Experimental Physiology, Laboratory of Physiology, Medical School of Athens, National &amp; Kapodistrian University of Athens.</span>
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					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
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									<p>This 2,5-week course will focus on cellular and molecular neuroscience. It will cover the mechanisms that operate to regulate neuronal excitability, dendritic and synaptic function; plasticity and neural circuits. This is an intensive course focused on cellular neurophysiology. The main aim of the course is to understand the principles of signal generation, modulation and transmission, both at the cell and circuit level.</p>								</div>
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									<p><strong>Learning Resource</strong><br />Kandel ER, Schwartz JH, Jessell, TM, et al. Principles of Neural Science 5th Edition (2012). McGraw-Hill NY. ISBN 0071390111</p>								</div>
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					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
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										<span class="elementor-icon-list-text">Introduction lecture</span>
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										<span class="elementor-icon-list-text">Ion channels</span>
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										<span class="elementor-icon-list-text">Membrane potential, Nernst Equation, Goldman Equation</span>
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										<span class="elementor-icon-list-text">Electrotonic potential</span>
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										<span class="elementor-icon-list-text">Passive membrane properties</span>
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										<span class="elementor-icon-list-text">Action potential</span>
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										<span class="elementor-icon-list-text">Na+, K+, and Ca++ channels and currents</span>
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										<span class="elementor-icon-list-text">Mechanisms of pre-synaptic release</span>
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										<span class="elementor-icon-list-text">Synaptic transmission - ligand gated and G-protein synaptic transmission</span>
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										<span class="elementor-icon-list-text">Neuromuscular Junction</span>
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										<span class="elementor-icon-list-text">CNS synaptic transmission 1- excitation Glutamatergic</span>
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										<span class="elementor-icon-list-text">CNS synaptic transmission 2- inhibition - GABAergic and Glycinergic</span>
									</li>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">CNS synaptic transmission 3- synaptic integration.</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Neural Circuits: methods of recording and analysis</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Modulation of Neural Circuits</span>
									</li>
						</ul>
						</div>
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				</div>
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					<h2 class="elementor-heading-title elementor-size-default">Titles of lectures and names of the lecturers</h2>				</div>
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									<table width="557"><tbody><tr><td width="39"><p><strong>A/A</strong></p></td><td width="387"><p><strong>Neurophysiology</strong></p></td><td width="131"><p><strong>Lecturer</strong></p></td></tr><tr><td width="39"><p>1</p></td><td width="387"><p>Cellular excitability, capacitance, input resistance, resting and action potentials, cable theory, voltage clamp</p></td><td width="131"><p>Christos Consoulas</p></td></tr><tr><td width="39"><p>2</p></td><td width="387"><p>NMJ &amp; Quantal Release</p></td><td width="131"><p>Christos Consoulas</p></td></tr><tr><td width="39"><p>3</p></td><td width="387"><p>Central Synapses: Excitatory and inhibitory, short and long term plasticity, paired pulse facilitation &amp; depression, LTP/LTD</p></td><td width="131"><p>Irene Skaliora</p></td></tr><tr><td width="39"><p>4</p></td><td width="387"><p>Neurophysiology of brain networks: methods of recording and analysis</p></td><td width="131"><p>Irene Skaliora</p></td></tr><tr><td width="39"><p>5</p></td><td width="387"><p>Calcium channels in synapses</p></td><td width="131"><p>Carsten Duch</p></td></tr><tr><td width="39"><p>6</p></td><td width="387"><p><strong> </strong></p></td><td width="131"><p><strong> </strong></p></td></tr><tr><td width="39"><p>7</p></td><td width="387"><p><strong> </strong></p></td><td width="131"><p><strong> </strong></p></td></tr></tbody></table>								</div>
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		<title>Gross and Microscopic Anatomy of the Nervous System</title>
		<link>https://masterneuroscience.gr/course/gross-microscopic-anatomy/</link>
		
		<dc:creator><![CDATA[LilyDanielyan]]></dc:creator>
		<pubDate>Fri, 17 Jun 2022 12:35:28 +0000</pubDate>
				<guid isPermaLink="false">https://coachfocus.qodeinteractive.com/?post_type=course&#038;p=5300</guid>

					<description><![CDATA[Teaching hours and weekly schedule This a 1st semester course of about 2.5 weeks that corresponds to 5 ECTs and 39 total hours of lectures. Co-ordinators &#160; Maria Panayotacopoulou Professor of Neurobiology, 1st Psychiatric Clinic, Medical School of the National &#38; Kapodistrian University of Athens Anastasia Tsingotjidou Assistant Professor, School of Veterinary Medicine, Aristotle University&#8230; <a class="continue" href="https://masterneuroscience.gr/course/gross-microscopic-anatomy/">Continue Reading<span> Gross and Microscopic Anatomy of the Nervous System</span></a>]]></description>
										<content:encoded><![CDATA[		<div data-elementor-type="wp-post" data-elementor-id="5300" class="elementor elementor-5300" data-elementor-post-type="course">
						<section class="elementor-section elementor-top-section elementor-element elementor-element-e4c990f elementor-section-boxed elementor-section-height-default elementor-section-height-default qodef-elementor-content-no" data-id="e4c990f" data-element_type="section" data-e-type="section">
						<div class="elementor-container elementor-column-gap-default">
					<div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-877fec7" data-id="877fec7" data-element_type="column" data-e-type="column">
			<div class="elementor-widget-wrap elementor-element-populated">
						<div class="elementor-element elementor-element-44b8d77 elementor-widget elementor-widget-heading" data-id="44b8d77" data-element_type="widget" data-e-type="widget" data-widget_type="heading.default">
				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Teaching hours and weekly schedule</h2>				</div>
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				<div class="elementor-element elementor-element-7b5733d elementor-widget elementor-widget-text-editor" data-id="7b5733d" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
				<div class="elementor-widget-container">
									<div class="bx-im-message-default-content__container bx-im-message-default-content__scope"><div class="bx-im-message-default-content__text">This a 1st semester course of about 2.5 weeks that corresponds to 5 ECTs and 39 total hours of lectures.</div></div>								</div>
				</div>
		<div class="elementor-element elementor-element-836ebfa e-flex e-con-boxed e-con e-parent" data-id="836ebfa" data-element_type="container" data-e-type="container">
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				<div class="elementor-element elementor-element-b9348e5 elementor-widget elementor-widget-heading" data-id="b9348e5" data-element_type="widget" data-e-type="widget" data-widget_type="heading.default">
				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Co-ordinators</h2>				</div>
				</div>
				<div class="elementor-element elementor-element-9b32813 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="9b32813" data-element_type="widget" data-e-type="widget" data-widget_type="icon-list.default">
				<div class="elementor-widget-container">
							<ul class="elementor-icon-list-items">
							<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="19" height="19" viewBox="0 0 19 19" fill="none"><path d="M17.1328 16L12.8203 18.8359L9.39844 12.9297L5.90625 18.8359L1.54688 15.9531L6 11.0078L0.140625 9.57812L1.73438 4.96094L7.33594 7.39844L6.91406 0.976562H11.9531L11.5312 7.39844L17.0391 4.96094L18.6328 9.57812L12.7734 11.0078L17.1328 16Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">Maria <strong>Panayotacopoulou</strong></span>
									</li>
						</ul>
						</div>
				</div>
				<div class="elementor-element elementor-element-35cd49a elementor-widget elementor-widget-text-editor" data-id="35cd49a" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
				<div class="elementor-widget-container">
									<p>Professor of Neurobiology, 1st Psychiatric Clinic, Medical School of the National &amp; Kapodistrian University of Athens</p>								</div>
				</div>
				<div class="elementor-element elementor-element-7a4ef7c elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="7a4ef7c" data-element_type="widget" data-e-type="widget" data-widget_type="icon-list.default">
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							<ul class="elementor-icon-list-items">
							<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="19" height="19" viewBox="0 0 19 19" fill="none"><path d="M17.1328 16L12.8203 18.8359L9.39844 12.9297L5.90625 18.8359L1.54688 15.9531L6 11.0078L0.140625 9.57812L1.73438 4.96094L7.33594 7.39844L6.91406 0.976562H11.9531L11.5312 7.39844L17.0391 4.96094L18.6328 9.57812L12.7734 11.0078L17.1328 16Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">Anastasia <strong>Tsingotjidou</strong></span>
									</li>
						</ul>
						</div>
				</div>
				<div class="elementor-element elementor-element-ee64889 elementor-widget elementor-widget-text-editor" data-id="ee64889" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
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									<p>Assistant Professor, School of Veterinary Medicine, Aristotle University of Thessaloniki</p>								</div>
				</div>
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							<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="19" height="19" viewBox="0 0 19 19" fill="none"><path d="M17.1328 16L12.8203 18.8359L9.39844 12.9297L5.90625 18.8359L1.54688 15.9531L6 11.0078L0.140625 9.57812L1.73438 4.96094L7.33594 7.39844L6.91406 0.976562H11.9531L11.5312 7.39844L17.0391 4.96094L18.6328 9.57812L12.7734 11.0078L17.1328 16Z" fill="#D74F4F"></path></svg>						</span>
										<span class="elementor-icon-list-text">Dimitris <strong>Mytilinaios</strong></span>
									</li>
						</ul>
						</div>
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				<div class="elementor-element elementor-element-8b51bbc elementor-widget elementor-widget-text-editor" data-id="8b51bbc" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default">
				<div class="elementor-widget-container">
									<p>MD, PhD, Medical Examiner, Medical School of the National &amp; Kapodistrian University of Athens</p>								</div>
				</div>
					</div>
				</div>
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Description:</h2>				</div>
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									<p>This is an intensive three-week course focused on neuroanatomy that includes lectures and laboratory sessions.  All material will focus primarily on learning the structure of the nervous system with a related focus on function for general neuroscientists.  Special attention will be given to chemical neuroanatomy in order to identify and describe the neurotransmitter systems of the brain and their connections. The goal of this intensive course is that students become well-versed in the structure and function of the nervous system in health and disease. Hands-on laboratory sessions will allow students to learn through direct experience.</p>								</div>
				</div>
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				<div class="elementor-element elementor-element-fc85f37 elementor-widget elementor-widget-heading" data-id="fc85f37" data-element_type="widget" data-e-type="widget" data-widget_type="heading.default">
				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Course Overview</h2>				</div>
				</div>
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									Interdisciplinary study of the nervous system, with the overarching theme that nervous system disorders can be understood in terms of neuroanatomical mechanisms.  The course covers general principles of the development, connectivity, neurotransmitter and receptor systems, blood supply, central nuclei and tracts of the central nervous system.								</div>
				</div>
				<div class="elementor-element elementor-element-4c228fa elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="4c228fa" data-element_type="widget" data-e-type="widget" data-widget_type="icon-list.default">
				<div class="elementor-widget-container">
							<ul class="elementor-icon-list-items">
							<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Major topographical features of the brain</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Describe the major anatomical subdivisions and functions of cerebral cortical systems</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Major interrelationships between primary brain structures</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and identify brainstem nuclei</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and identify brainstem tracts</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and identify major somatomotor systems</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and identify major somatosensory systems</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and identify central sensory systems (visual, auditory and vestibular pathways)</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and understand cranial nerves</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Understand and localize hypothalamic subnuclei and autonomic systems</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Understand and localize the limbic system and diencephalon</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Understand and localize the basal ganglia</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Localize and identify the blood supply of the brain, the ventricular system and meninges</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Understand the basic immunohistochemical methodology that permits the localization of neurons on the basis of their neurotransmitter expression</span>
									</li>
								<li class="elementor-icon-list-item">
											<span class="elementor-icon-list-icon">
							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Understand the basic concept of in situ hybridization for the study of gene expression in chemically identified neurons that permits the molecular investigation of the nervous system in health and disease.</span>
									</li>
						</ul>
						</div>
				</div>
					</div>
				</div>
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				<div class="elementor-widget-container">
					<h2 class="elementor-heading-title elementor-size-default">Skills &amp; Learning Outcomes</h2>				</div>
				</div>
					</div>
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				<div class="elementor-widget-container">
									<p>Interdisciplinary study of the nervous system, with the overarching theme that nervous system disorders can be understood in terms of neuroanatomical mechanisms.  The course covers general principles of the development, connectivity, neurotransmitter and receptor systems, blood supply, central nuclei and tracts of the central nervous system.</p>								</div>
				</div>
				<div class="elementor-element elementor-element-33f19af elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="33f19af" data-element_type="widget" data-e-type="widget" data-widget_type="icon-list.default">
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							<ul class="elementor-icon-list-items">
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										<span class="elementor-icon-list-text">Describe and identify the components of the nervous system and the sensory organs.</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Identify the structures of the brain, spinal cord and peripheral nervous system.</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Describe the relationship of the structure of the nervous system to its functions: movement, sensory systems- basic functions of a living organism.</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Describe the relationship of the structure of the nervous system to its functions: movement, sensory systems- basic functions of a living organism.</span>
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										<span class="elementor-icon-list-text">Describe and identify the structure and functions of the autonomic nervous system and the cranial nerves.</span>
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							<svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 10 10" fill="none"><circle cx="5" cy="5" r="5" fill="#D74F4F"></circle></svg>						</span>
										<span class="elementor-icon-list-text">Relate the chemical and molecular anatomy of the nervous system to clinical syndromes and diseases.</span>
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					<h2 class="elementor-heading-title elementor-size-default">Titles of lectures and names of the lecturers</h2>				</div>
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									<table width="567"><tbody><tr><td width="47"><p><strong>A/A</strong></p></td><td width="369"><p><strong>Gross and Microscopic Anatomy of the Nervous System       </strong></p></td><td width="151"><p><strong>Lecturer</strong></p></td></tr><tr><td width="47"><p>1</p></td><td width="369"><p>White matter Tractography</p></td><td width="151"><p>Foteini Christidis</p></td></tr><tr><td width="47"><p>2</p></td><td width="369"><p>Topographic anatomy of the cerebral cortex-functional mapping</p></td><td width="151"><p>D.Mytilineos</p></td></tr><tr><td width="47"><p>3</p></td><td width="369"><p>Functional Neuroanatomy of Cognition </p></td><td width="151"><p>N. Foroglou</p></td></tr><tr><td width="47"><p>4</p></td><td width="369"><p>Structures and Mechanisms of Language</p></td><td width="151"><p>C. Potagas</p></td></tr><tr><td width="47"><p>5</p></td><td width="369"><p>Hypothalamus and the pituitary gland</p></td><td width="151"><p>M. Panayotacopoulou</p></td></tr><tr><td width="47"><p>6</p></td><td width="369"><p>Structure and function of the limbic system</p></td><td width="151"><p>K.Tsamis</p></td></tr><tr><td width="47"><p>7</p></td><td width="369"><p>Brain Stem and Cerebellum</p></td><td width="151"><p>D. Mytilinaios</p></td></tr><tr><td width="47"><p>8</p></td><td width="369"><p>Thalamus</p></td><td width="151"><p>D. Mytilinaios</p></td></tr><tr><td width="47"><p>9</p></td><td width="369"><p>Basal Ganglia</p></td><td width="151"><p>M. Xilouri</p></td></tr><tr><td width="47"><p>10</p></td><td width="369"><p>Spinal Cord and pathways (+ autonomic NS)</p></td><td width="151"><p>A.Tsingotjidou</p></td></tr><tr><td width="47"><p>11</p></td><td width="369"><p>Hearing and balance</p></td><td width="151"><p>E. Anagnostou</p></td></tr><tr><td width="47"><p>12</p></td><td width="369"><p>Chemical and Molecular Neuroanatomy/ Electron Microscopy</p></td><td width="151"><p>M.Panayotacopoulou,       M. Chrysanthou</p></td></tr><tr><td width="47"><p>13</p></td><td width="369"><p>Vision and Visual Cortex (+ plasticity)</p></td><td width="151"><p>E. Skaliora</p></td></tr><tr><td width="47"><p>14</p></td><td width="369"><p>Microscopic Anatomy of the Human brain</p></td><td width="151"><p>M. Panayotacopoulou,  M.Chrysanthou</p></td></tr><tr><td width="47"><p>15</p></td><td width="369"><p>Gross and Microscopic Anatomy of the rodent brain</p></td><td width="151"><p>A. Polysidi/ M.Xilouri</p></td></tr><tr><td width="47"><p>16</p></td><td width="369"><p>Comparative Neuroanatomy (pig, sheep, rodents)</p></td><td width="151"><p>C. Bekiari/A.Tsingotjidou</p></td></tr><tr><td width="47"><p> </p></td><td width="369"><p> </p></td><td width="151"><p> </p></td></tr></tbody></table>								</div>
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